Concluding comment: New approaches to cancer therapy and prevention

Genetics and new approaches to cancer therapy.

The past two decades have been golden years for the genetics of cancer. It has become clear through the work of countless laboratory groups that both inherited and sporadic cancers arise through defects or misregulations of their genomes. Several dozen dominantly acting oncogenes have been identified, shown to be deregulated in human tumors and to positively influence one or another aspect of t...

New approaches to HIV prevention.

Just as the 1996 International AIDS Conference in Vancouver ushered in the era of effective combination antiretroviral therapy and the 2000 meeting in Durban focused on the HIV/AIDS epidemic in the developing world, the 2006 conference (held August 13-18 in Toronto) may be remembered as the one that brought HIV prevention to the fore. Political considerations aside, it has become abundantly cle...

New approaches to shoulder surgery: editorial comment.

The shoulder is a fascinating joint. The combination of mobility and stability of the shoulder allows us to position the upper extremity in space so that we may accomplish a large variety of functions. A wide array of pathological entities affect the shoulder, ranging from arthritis to instability and including the rotator cuff, scapular muscles and other joints in addition to the glenohumeral ...

Preface: New Immunological Approaches to Cancer Therapy Dedicated to Dr

Lifestyle and medical approaches to cancer prevention.

Cancer risk can be reduced by adopting a healthy lifestyle and by medical means. Tobacco control is central to public policies for cancer prevention. Overweight and obesity in the United States may contribute to 20% of cancer deaths in women and 14% in men. Cancer prevention strategies have progressed from a predominant lifestyle approach to a model that combines clinical investigations in a me...